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Oral metronidazole has been described to potentiate the anticoagulant influence of warfarin and other coumarin anti‑coagulants, leading to a prolongation of prothrombin time.
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METROGEL-VAGINAL affords nominal peak serum concentrations and systemic exposure (AUCs) of metronidazole as compared to 500 mg oral metro‑nidazole dosing. Though these reduce amounts of publicity are more unlikely to supply the common reactions observed with jnetoto oral metronidazole, the opportunity of these and other reactions cannot be excluded presently.
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The following adverse reactions and altered laboratory assessments have been reported Together with the oral jnetoto or parenteral usage of metronidazole:
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